Trifarotene is a white to off-white to slightly yellow powder with a melting point of 245°C. It is practically insoluble in water with pKa1 of 5.69 and pKa2 of 4.55.
AKLIEF (trifarotene) Cream 0.005% contains the following inactive ingredients: allantoin, copolymer of acrylamide, and sodium acryloyldimethyltaurate, dispersion 40% in isohexadecane, cyclomethicone, 5% ethanol, medium-chain triglycerides, phenoxyethano.
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